How many follicles for iui twins Tomorrow (CD 11) is our follicle scan. Design: Prospective randomized trial. 000 in Brazil. 5% - 2. I’d be comfortable with 3 follicles knowing I could have twins, but anymore than that scares me! #dontwanttobeoctomom So my question is - what has been your experience in your number of follicles before your IUI? See Will Clomid Make You Have Twins? for more information. My clinic triggers when You may be more likely to have twins or triplets. 8% in the presence of an additional follicle measuring 12 mm or wider or 14 mm or wider, respectively. We had been with my clinic for over a year so they were okay triggering. With a single embryo transfer, the likelihood of a twin pregnancy is about 1%. the day before my iui the drs said that I had 6 mature follicles. 2009 - 1 cycle of Femara - No O Mar. I had one follicle in range (19mm) and two 12mm follicles. 7% to 24. The first and most common risk is getting pregnant with multiples (twins, triplets, etc. When Clomid is used, the risk of Stop me from worrying! I had 6 follicles yesterday on Cd 12. How many ladies's there currently on puregon 50ml and IUI? This will be mine round two IUI and round one with injectible medication, clomid has'n worked for me in 3 rounds even I responded well to it. 27+4 currently! Which of you had more than 2 follicles before IUI? Did your doc give an opinion one way or the other about whether you should proceed given the risk of multiples? Anyone respond too well to 50 mg of clomid (10-11 follicles) but more normally when clomid was reduced (1-2 follicles)? That does seem like a lot! I just had my ultra at CD 12 and I had 4 dominant follicles ranging between 16-22. My clinic monitors follicle growth, estrogen and progesterone. Then I did a similar protocol with 3 mature and iui and finally got a positive. Started at 35 years old. How many mm do follicles grow each day? In general, most follicles will grow about 1-2 mm per day, but this can vary among patients. Generally, IUI is a very safe procedure. Statistically fertility treatments overall increase your Monitor the follicles. Sasson, while a person in their 20s can have as many as 20 follicles each month, that number may fall to 15 for a person who is 35, and then around eight to 10 at age 40. They can't always see all the follicles on scans, after all. I haven’t yet Today was my cd12 scan, I was told to trigger tonight and iui noon Tuesday. I haven’t yet had my first u/s. We did 5 IUI cycles: all with trigger shots, 4 with Clomid. Typically, doctors will want to see one or two follicles in the 18-20mm range at the time of trigger. This time I did another round of injections with trigger shot and again donor sperm. I am getting ready if all ok for IUI at the end of this week. 4% per cycle and decreased with age. This last iui I had 3 on my 11 day scan (23,18,16mm). References Background: The influence of multifollicular growth on pregnancy rates in subfertile couples undergoing intrauterine insemination (IUI) with controlled ovarian hyperstimulation (COH) remained unclear. 5 I had few eggs but on small side. It is important to note that IDENTICAL twins come from one egg that splits, so multiple follicles are not an issue there. Obvious factors are number of follicles and peak n = 11 or 11. The cycle with 1 follicle was successful. I understand from your OP that you are nowhere near this situation, nor have you done an IUI with more than 1-2 follicles. However! If you have 2 corpus luteums, that means that you did indeed release 2 eggs and you have a higher chance of fraternal twins. I did loose one early on, but am currently 28 weeks with twins. New RE recommended switching to IVF. Pregnant with 1 baby but ended in early MMC sadly. We did 10 medicated cycles, the last 4 were IUI and Pregnyl trigger. And of all multiple births, twins—as opposed to other sets like triplets or quadruplets—accommodate for 97%. 3. How many cycles did you do before your BFP? With DS I got pregnant on my first IUI cycle, with this pregnancy I got pregnant on my second IUI cycle. There’s a really good chance you have 4-5 mature follicles (depends on the individual but a 14 mm follicle can definitely produce a mature egg). Report as Inappropriate. With an IUI you would never really know how many eggs were mature, and looking at 6 you could easily have 8+ if your E2 levels are rising appropriately. Research ranges on the chance of success, but, on average, chance of success per IUI is IUI is low risk compared to other more invasive fertility treatments like IVF. First pregnancy with femara was a singleton but resulted in a missed miscarriage and this last one we had twins. The most mature follicles I ever had with an IUI was 3. What are the chances of twins In IVF as compared Find out what you need to know about trigger shot IUI for fertility treatments. That does seem like a lot! I just had my ultra at CD 12 and I had 4 dominant follicles ranging between 16-22. We will see tomorrow how many follicles I have, Yep. I had 5-6 mature follicles with femara and gonal f and did a timed intercourse cycle resulting in an negative. Typically, women can have 1 to 30 visible follicles in each ovary at the start of their menstrual cycle. 4 follicles would be 1% chance of quads, 10% chance of triplets and 30% chance of twins! I had IUI with 4 follicles, 3 implanted, but 2 became vanishing twins. IUI is not likely to work if you have severe fertility problems. I had I’ve done 3 IUIs so far with Letrozole 5mg, including one where I had 2 mature follicles, Currently pregnant with a singleton from a two mature follicle cycle of Letrozole and have previous twins from a four mature follicle round of injectables. You can still test your trigger but don’t be surprised if A monitoring visit (commonly referred to as your cycle day 12 ultrasound) will give us all of that information. Has anyone gotten pregnant with follicles In a Letrozole medicated cycle, the amount of FSH a woman produces increases which may cause multiple follicles to develop and multiple eggs to be released, Gonadotropin medications may also be used with an My clinic measures a mature follicle as being right around 20mm. There Does anyone know what there follicle size was before they found out the were having twins?I am on femara 2. To reduce this risk, it is especially important How many follicles do you normally have on 50mg Clomid? Unmediated I always have one dominate follicle. The rate of twins in the general population is around 1%. In other words, 4% of all the pregnancies achieved with 1 follicle were twin pregnancies, and 12% of all the pregnancies achieved with 2 follicles were twin pregnancies. 3rd - 3 mature follicles (all from same side), successful and currently 37w with di/di twins! After 5 cycles that failed (3 that had 2 follicles; 1 cycle with 1 follicle and 1 canceled cycle with 5 follicles), I produced 3 mature follicles on a letrozole and gonal f cycle. There were 3-4 follicles and the twins are fraternal. Ovulation induction medication is also frequently used to stimulate extra follicles to develop in the ovaries of women that already ovulate IUI procedures have yielded success for many women and couples, and going into the process with as much understanding as possible can help you feel empowered and ease your worries While IUI is the process of injecting sperm directly into the uterus, a number of factors and decisions accompany the cycle that determine the logistics of a cycle, along with its rate of success, risk, cost and burden. The rate of twins with Femara treatment is around 3. The probability of each egg being fertilized and implanted is still around 30% each. 7. The chances of conceiving twins on clomiphene citrate TTC since 11/2006 2007 - 3 cycles of Clomid - No O 2008 - off Feb. IUI 2 was cancelled (sperm lost in mail). This time we have tried iui again. He is joining me to talk about when you should consider canceling your IUI. 26 Comments How many follicles did you have? 2. So with 4 chances, I got a singleton pregnancy and at my first ultrasound, it looked like one of the “follicles” turned out to be a cyst. I triggered Ovitrelle 36H before the IUI, and again But yes, you need to be prepared mentally that you could conceive twins or triplets, in theory. We have unexplained infertility and my husband's sperm count was also usually high but could be very variable (he's 44 and has a 16 year old son with his ex). 3rd - 3 mature follicles (all from same side), successful and currently 37w with di/di twins! The most they ever let me have was 2 follicles for IUI. 2 other unsuccessful attempts. Discover Once your ovarian follicles show the desired Increased chance of multiple Not IUI, but I conceived twins using letrozole and TI (no trigger). I am just curious how many follicles you ladies had at time of IUI and if you got your BFP did it result in multiples? I am terrified that if we decide to do IUI, If you are one of the lucky 20% who conceive, you then have a 20% chance of twins and a 1% chance of triplets. Unfortunately, Having multiple follicles will increase your chances, but some people get twins from one egg, just like non-triggering people do. I did 2 rounds of IUI with gonal f and ovidrel trigger. I am 11 weeks pregnant with twins from IUI. How many follicles do you normally have on 50mg Clomid? Unmediated I always have one dominate follicle. ). The present study highlights the impact of multiple clinical factors on IUI success, (LH) surge kits or follicle tracking ultrasounds. 7%. That's because women who have a multiple pregnancy (carrying more than one baby) are at a higher risk for complications, including preterm birth, low birth weight, preeclampsia (high blood pressure), gestational diabetes, and a cesarean birth. b What the Number of Ovarian Follicles Says About Fertility. All were released at ovulation. We also had 3 follies, two implanted. So I'm happy to be pregnant but it's bittersweet til everything is settled. Other factors that increase the chance of a twin pregnancy are weight, age, and family history. These data may help clinicians balance decision-making between cancelling Personally, I’ve done IUIs with three follicles despite not wanting twins - but only after multiple failed IUIs with one and two follicles. I don't remember for three, sorry! I'm excited Congratulations!! I’ve done 3 IUIs, and here’s how they went: 1st - 4 mature follicles, doctor warned against risk of multiples but we went ahead. Switched clinics. To reduce this risk, it is especially important An IUI cycle can be broken down into a few simple steps, which take place over a typical menstrual cycle. Not using I am doing Follistim and IUI. 2 mature follicles definitely means you have a chance of having twins, no doubt. I had one follicle at 22 and the left and a 17 on the right, both took. The successful one was 100mg. If there are more than 2 large ones Im on my first IUI and I'm in the oh so long "2 week wait" lol I was wondering how many IUI you had to do before you were dobberkins IUI #7 = b/b twins 7/16, Ovulated early on my first Second IUI - Day 11 scan- multiple follicles. 000 - R$8. And if you are pregnant, chances for twins are about 15% for I loved menopur. For context, compared with IVF , IUI delivers significantly lower live birth rates (2 - 10x lower) and potentially far-higher (8 - 30x) rates of multiple-births-per-pregnancy. The first round I only had 1 follicle and I think I had 2 the second round. 3%, P<. Last Friday on feb. Second month I did 112. hello ladies! this cycle, i took 50mg of clomid days 4-8 and had 3 mature follies that all ovulated. 8 CM I knowHow many hours after your trigger was your IUI? 36How many motile sperm did you have post wash? 9 mil post thaw. More info on cancelled cycles can be found here. Follicle monitoring with transvaginal ultrasound will verify that you have an appropriate number of follicles developing. There is always a She said I have 4 follicles that are each about 17 or 18 (I'm not sure what this means exactly other than that this is what they want). I had two follicles and I remember leaving the office crying bc I only had two. Best of luck at your RE appointment! What are the chances of twins or triplets with IUI? Because these ovary stimulating medications cause many follicles to mature and ovulate, leading to a higher risk of twins, there are about 10-12 percent chances of twins. (2) multiple pregnancy occurring: With Clomiphene, the risk of twins is about 8% and the risk of triplets is about 0. meganhandler. Amongst the pregnant patients 284 were Overall, IVF provides multiple fold higher pregnancy rates as compared to IUI, as well as, a multiple gestation rate that is much lower because of the use of single embryo transfer. On that cycle I only had 1 dominant follicle. An analysis of multiple studies came to a similar For my IUI's. The last time my doctor saw me she said that we could do "Follistim. Clomid or Letrozole are taken to grow follicles containing eggs, follicles are tracked via ultrasound, and a trigger shot induces ovulation which times the insemination process. The first 2 cycles failed, the 3rd worked but I had a CP, the cycle directly after we did the whole process again but added Progesterone and baby asprin and I am currently 29 weeks pregnant with boy girl twins! An ultrasound around the time of ovulation will reveal exactly how many follicles are being released. How many follicles did you My clinic measures a mature follicle as being right around 20mm. With one large follicle, the twin pregnancy rates ranged from 1. 6%), 8 underwent elective fetal reduction (7 to twins and 1 to a singleton), and all have found that the number of follicles predicted multiple Larger follicles may indicate a higher potential for multiple egg releases during ovulation, increasing the likelihood of fraternal twin conception. If too many follicles develop during your IUI cycle, your treatment may have to be stopped because of the risk of a multiple pregnancy. TTC#3 July 2014 - Metformin +TI = BFP at 9dpo - Twins, one baby lost at 5. We are switching to IVF now with me as GP, which is a decision we never ever expected to make. IUI Ladies - how many follicles is too many? j. 9-23. A meta-analysis was performed and Mantel-Haenszel pooled odd According to Dr. I had 2-3 mature follicles and ended up pregnant with b/g twins. You make three or four visits to the The second pregnancy, I only had one follicle and now I'm 33wks along. In that case, fraternal twins would result. I am now 6 weeks pregnant with twins. 10/10 would recommend ;) No we still used a trigger, the gonal-f was used before the iui. Like. i'm pretty sure i'm not pregnant, so back to the Clinical pregnancy rates ranged widely from 3. Dr. Lucky shares 10 essential IUI facts that can boost your chances of success. After the sperm wash my husband had 28 million sperm with high motility and the dr said our numbers were outstanding Today was my cd12 scan, I was told to trigger tonight and iui noon Tuesday. But two really good follicles! I always recommend menopur!!! Last Friday on feb. IVF treatment is more effective and safer. We were originally pregnant with twins but lost Baby A at 10 weeks my follicles were 24mm, 22mm and 16mm at trigger. multiple pregnancy occurring: With Clomiphene, the risk of twins is about 8% and the risk of triplets is about 0. Because of the multiple eggs that are produced with IUI, there is a risk of having more than one baby. They advised me to give myself the trigger shot that day so the follicles wouldn’t grow further. Did 3 medicated IUIs with donor number 1. I won't know until next week how many took. Reply . Kate Gosselin had her sextuplets on an IUI cycle with only 4 follicles - and she actually had seven but one fetus failed to develop. I took 5mg all 3 rounds of IUI we did since I have PCOS and wasn’t ovulating on my own. In women under 35, increasing the number of follicles from 1 to 5 increased clinical pregnancy by 7. Triplet pregnancies are rare with oral medications. DH had 36million Background: Although the number of follicles at intrauterine insemination (IUI) is associated with the pregnancy rates and multiple pregnancy rates. Our goal is to grow ~2-3 follicles to ~18 mm in size before doing an oocyte retrieval. June 28, 2024 | by Ttciui. In this age group, patients with 3 or more follicles, 21% of all pregnancies were Because having multiple follicles growing during an IUI cycle puts you at a higher risk of having a multiple pregnancy, physicians try to avoid recruiting too many follicles for an IUI cycle. Identical twins are spontaneous so no increase in chance of having twins there. 5 years with multiple failed IUI’s. How many follicles is ideal for IUI and how many follicles can there be before the provider cancels a cycle because the risk of multiples is too high (obviously I get this varies from each provider). My first IUI we had three small follicles develop, all under 20 at time of trigger resulting in no pregnancy. Research indicates that a healthy woman in her reproductive years generally has around 15-20 antral follicles in each ovary at the beginning of her cycle. 5%) twin pregnancies occurred in cycles with at least one additional follicle measuring 12 mm or wider, and 102 out of 127 twin pregnancies (80. 4% for clomiphene, although this was not statistically significant. This is much higher than Mother Nature provides at approximately 2%. This second iui, I did metformin, clomid 100mg days 5-9, had a trigger on cd13, When is the trigger shot administered in the IUI process? The trigger shot is typically administered after ovarian stimulation medications have been used to stimulate With 2 follicles on Clomid, the studies vary but seem to hover over 10% chance of twins. Did 1 round of egg retrieval with donor number number 2. I'm a little As a result, the brain produces more follicle stimulating hormone (FSH), which stimulates the growth of multiple follicles. Your body should choose to release the "best" (and usually biggest) follicle. I have done 5 IUIs. No IUI. It’s crucial to have a clear plan with your doctor about how many mature follicles Gonadotropins, which stimulate egg follicle growth and are usually injected during IUI, also increase the chances of multiple births. You should have an in-depth conversation about personalized risk with your physician before starting an IUI cycle, as detection of multiple follicles may be a reason to cancel the IUI cycle. Currently pregnant with twins from an injectibles+IUI cycle with 2 dominant follicles- except that I initially conceived While IUI alone will not increase the risk of twins, the use of fertility medication does make it more likely that patients will have a multiples pregnancy. I just got a BFN on my first IUI, but I did have one follicle that was 24x18 and another that was 15x9. However she said these are too many to do the insemination 2. A twin/triplet/etc pregnancy increases the risk of certain health issues for the mother and the babies, so physicians usually try to aim for just one Background: The influence of multifollicular growth on pregnancy rates in subfertile couples undergoing intrauterine insemination (IUI) with controlled ovarian hyperstimulation (COH) remained unclear. IUIs can work! Best of luck!! Like. 17,2017 I had my first iui. S. With 2 follicles on Clomid, the studies vary but seem to hover over 10% chance of twins. In contrast, the chance of a twin pregnancy after IVF depends on the number of embryos transferred. Everyone is so different and it’s so hard to Child 1 is a Clomid/TI baby. Since in cycles with three or four follicles the multiple pregnancy rate increased without There is abundant evidence that suggested using one or two follicles in IUI is sufficient and safer than multiple follicles. Ovulation induction medication is also frequently used to stimulate extra follicles to develop in the ovaries of women that already ovulate IUI procedures have yielded success for many women and couples, and going into the process with as much understanding as possible can help you feel empowered and ease your worries All ovulation medications increase the risk of twins, and injectible medications increase the risk of triplets and higher order multiple gestations. Multiple pregnancy rates are low in older The combination of washed sperm and fertility drugs largely enhances the fertilization of multiple eggs in an IUI cycle. A total of 73 out of 127 (57. As we mentioned, while this “multiples-per-pregnancy” rate is high, since IUI has such modest pregnancy rates, only 0. We have been trying for 6 months, three failed IVF and 3 failed IUI (but for the last one which resulted in a chemical pregnancy). We also used a trigger shot for each round. How many mature follicles resulted in your fraternal twins?I am 5 weeks pregnant. I had 8 follicles, I think 3 were larger, my doc talked about twins. If there are too many mature We used letrozole along with IUI. It stimulates the secretion of follicle-stimulating A twin pregnancy appears to be more common with Clomid having a thin uterine lining is associated with a lower pregnancy rate after IUI. On my 3rd and final round i got pregnant with twins, a boy and a girl! I couldn’t be happier. 6%, P<. In this scenario, the ovaries would create too many follicles to safely proceed with IUI Did anyone have IUI success with smaller follicles? How many IUIs did you do? Tell me your success stories and stats. They're also a risk for IVF. I’d be comfortable with 3 follicles knowing I could have twins, but anymore than that scares me! #dontwanttobeoctomom So my question is - what has been your experience in your number of follicles before your IUI? Due to the much higher risk of twins and high-order multiples, most physicians recommend patients consider proceeding to IVF if they have failed prior IUI cycles with oral medications The cost of a gonadotropin IUI cycle can be around $2,500 per cycle. Sasson, while a person in their 20s can have as many as 20 follicles each month, that number may fall to 15 for a person who is 35, and then around eight I'm Fostimon injections, and at my 2nd scan yesterday (day 10) they said I have 1x14mm follicle, 2x 13mm follicles and 3x 10mm follicles. 2 Similar Discussions Found . Natural cycles do not require monitoring, but if monitoring is done, a woman comes in on cycle day 3 for a baseline ultrasound, returns back 4 days before ovulation is expected, and can either be “triggered” when the I can talk about this for hours LOL. What number IUI did you get your first BFP? #4At your last monitoring appointment, how many follicles did you have and what were their sizes? 3 follies atleast 1. 3%. If your doctor feels that Clomid is right for you, you’ll likely start with a dose of 50 milligrams (mg) per day. Blake Evans of University of Oklahoma Reproductive Medicine in Oklahoma City. m. Twins are always a chance with Clomid and multiple follicles but with PCOS typically having less than great egg quality you’d be lucky to get one. 3%) occurred in cycles with at least one additional follicle measuring 14 mm or wider. On day 13th I had my u/s nd had 3 matured follicles ( 19mm, 17mm & 16mm) nd 7 unmatured less than 14mm so Dr suggested to drop this cycle due to chances of multipe preg When you take Clomid, your body makes more follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The Just wondering how many follicles you had when you had your iui, and whether you ended up with twins!I had 2 follicles when I triggered and recently had a BFP. The first I took 150mg Clomid CD 5-9CD 11 u/s showed 11mm lining and 2 mature follicles (24mm and 27mm). 8 percent. I have IUI twins. There are so so many women triggering with a 20+ mm follicle and fuss about not being pregnant. The presence of a 12-mm follicle is a risk factor for twin pregnancy after IUI procedures (Table 3). A doctor or nurse will perform a transvaginal ultrasound that will allow them to see how many follicles you have developed after taking the medication and therefore, how many eggs you will likely ovulate. 01 and 0. If we suspect this might be the case, One concern is that you could have a multiple pregnancy (twins, triplets, or more). With Letrozole, the risk of twins is less than 5% and the risk of triplets very low. I had IUI three years ago with injections and a trigger shot. IVF success rates are higher compared to the superovulation IUI success rates. 6% to Multifollicular growth is associated with increased pregnancy rates in IUI with COH. IUI is one of the first assisted reproductive technologies typically recommended by a doctor. Have you thought of doing more then just the 3 IUI's? I know many women do more and end up with successful pregnancies. Triplets or higher order pregnancies can occur, but are much less frequent; only 1-3% of pregnancies. In natural conceptions, multiple births occur about 1. If the statistics don't chance too much for higher multiples, that would mean 3 follicles We are doing our first IUI. 2nd IUI resulted in we’ve been trying for 2. If the statistics don't chance too much for higher multiples, that would mean 3 follicles would be around 3% chance of triplets and 15% chance of twins. Cycles that include gonadotropins have 8 - 10% live birth rates, 8 - 30% multiples-per-pregnancy, and cost $4,000 in the U. They made sure I was okay with the possibility of a multiple baby pregnancy also. I had 1 follicle for round 1 and none for round 2! So you don't always get multiple follicles, and there may be no rhyme or reason why some people get multiple while others don't. Follicles are We just confirmed this morning that we're having twins after 50 mg of Clomid, trigger and IUI. I had a monitoring ultrasound 2 or 3 days before the iui and I only had 1 mature follicle. When we got pregnant one our Did you do IUI and get a positive? How many follicles did you have? Did you get pregnant with multiples? Thanks! Like. and R$3. This allows your provider to see how many and how large your follicles are growing in response to the medication. Are you willing to risk twins? If so, I'd say go for it. Cancellation criteria should consider the presence of follicles 12 mm or wider. 2nd - 2 mature follicles, failed. With the trigger shot, this rate . But we were never ready to cancel. For my body, I was able to get more follicles if I took it on day three compared with starting on day four or five. The pregnancy rate with IUI and no trigger shot was 5. 5 year old son. My wife is 34, 100% normal test results. Child 1 is a Clomid/TI baby. We will be doing a trigger shot this cycle as well. I had 3 mature follicles (29, 22, 17) but found out after my husband gave a I am 4w5d along after my second iui. Hi we had di/di twins with iui, 100 mg clomid on days 2-6. There were definitely 3 mature follicles on my left. I had one mature follicle and it was fertilized with donor sperm and I now have my 2. Congratulations!! I’ve done 3 IUIs, and here’s how they went: 1st - 4 mature follicles, doctor warned against risk of multiples but we went ahead. pregnancy tests turn positive based on HCG, and every woman's baseline hcg( where she is normally when not pregnant) varies from a 1-5. We are pregnant with twins after IUI. All unsuccessful. We were given a 5% chance of the IUI working due to low sperm count. After IUI#1, I was very down and convinced that if the first one didn't work, IUI was never going to work for us. In this case infant mortality rates and delivery bleeding rates rise 5 - 10 fold. Hcg was 11 so the nurse thought it was on the way back down. 9) and secretly hoping for twins. The second round I had 3 mature follicles and it was successful. Fraternal twins here. 5 went in for u/s cd14 folly size were 18 and 23. there is a 3-8% chance of conceiving twins or higher-order multiples. 2009 - Femara and Physicians have long sought ways to predict pregnancy and multiple gestations during gonadotropin-IUI. 4 and one 17. On 50mg I have 2 dominate (normally one on each ovary). These hormones work to stimulate ovulation and may result in more than one egg being released, which can cause a multiple pregnancy. 6% to Hey Ladies! My 2nd IUI will be done in November if we dont get pregnant this cycle. 1. Ended up with di/di twins. My last 2 (with 3 and 4 follicles) were BFPs with only 1 baby but we lost both of them. The first round I had 5 mature follicles at the time of IUI and it was unsuccessful. I was successful with fraternal twins on my second IUI! I did clomid + trigger shot then had sex the evening of the IUI as well. On a day 11 scan in a cycle with 100mg Clomid I have five mature follicles - 15/15/16/16/18. What is the risk of twins with Femara? A 2014 study found that the rate of twins with Femara was 3. The degree to which an IUI cycle is demanding depends on the decision of which (if any) drugs are taken and whether the cycle is accompanied by monitoring. Some of the risks of IUI are: Multiple births: You might release more than one egg if you take fertility medication. I had one follicle 19. 6% to 11. 6%), The Clomid would make you have 2 follicles which would increase your chance of multiples if you are doing IUI because you aren't controlling the fertilization as you would with Hope you don't mind me sneaking in for a question. Follicle monitoring, which involves several internal ultrasounds in the lead-up to ovulation, will show how many mature follicles you are producing. In Everything IUI. The first time around, we did 3 cycles on both Clomid and injections, and each cycle produced 3-4 follicles. I only had 2 mature eggs as trigger On my first all-injectable cycle, I had one mature follicle, and did back-to-back IUIs at 14 and 38 hours past trigger. Let's learn! The presence of a 12-mm follicle is a risk factor for twin pregnancy after IUI procedures (Table 3). Second IUI we had two large follicles, around 22 at trigger and that’s the one we got twins on. In this procedure, the increased chances of twin pregnancies depend upon the number of embryos you choose to transfer. My clinic cancels if there are more than 3 or 4. In women completing ultrasound monitoring, ovulation was triggered with human chorionic gonadotropin (hCG) when the lead follicle measured 20 mm. (2) What is the risk of twins with IUI? The twin risk with oral medication and IUI is approximately 10%. t. 5 on gonal f and four days of menopur. My stats over 4 IUIs were 2/1/3/2 follicles and For those who have done IUI, how many dominant follicles did you trigger with? I went in for a CD10 ultrasound and had 5 dominant follicles between 16-18mm with 3 more in the 12-14mm range. 01 each). This morning I learned from the doctor that I am ready to go on Wednesday with IUI but that my body responded very well to the meds this time and I If we detect two mature follicles on ultrasound, the chance of twins occurring is slightly increased. Baby dust to all. As mentioned earlier, the chances Follicle sizes don't determine whether the egg is mature or not. Used femara. The sex as well that night is my superstitious "reason" IUI#2 worked, since we didn't do that with IUI#1. I had a round of Clomid 3-7 and a trigger shot the same day my lh strip was positive. 4%. most at home pregnancy tests measure anything above a 25 as a positive, only a blood What are the chances of twins or triplets with IUI? Because these ovary stimulating medications cause many follicles to mature and ovulate, leading to a higher risk of twins, there are about 10-12 percent chances of twins. I had Identical twins are just by chance. Likelihood of a singleton pregnancy per IUI rose modestly (from 14. A meta-analysis was performed and Mantel-Haenszel pooled odd I did 3 IUI using gonal f only the 1st month @187. We accepted the higher risk of multiples when we added injectables into our cycles, and our clinic has a strict policy of canceling any cycles with over 3 follicles maturing. 2 at 26, 1 at 24, and 3 23s. I also have multiple twins in my family so I knew the risk regardless. 1-18 mm 3- 16/17 mm 2-14 mm The OB said it was my call whether or not to trigger, and That said, a 2017 study " on IUI cycles compared cycles with a trigger shot to ones without it. Good luck and baby dust One common question many women have is how many follicles are normal in each ovary. No idea how many follicles as it was an unmonitored cycle, but I do only have 1 Fallopian tube. I ovulated on 2/15 and had my iui on 2/16. What are the success rates with Clomid with and without IUI #2 and #3 involved Gonal F shots and triggering Ovitrelle. Patient(s): Women <40 years old, with patent fallopian tubes and infertility of >1 year in duration. @roetik77, I did 6 IUIs total. My fraternal twins are just over 8 months old. Is that about right for 50mg Clomid? I ovulate normally but we have MFI and trying to get How many mature follicles resulted in your fraternal twins?I am 5 weeks pregnant. ° Multiple pregnancy - Twin pregnancies occur in 1-2% of naturally-conceived pregnancies. Larger follicles are always more likely to grow compared to smaller ones. I had my follicle scan this morning and have 4 follicles growing: 21,19,17,15 mm. It was the third attempt after a few trials, this was the second with injectables. I had two other follicles that were at 12 and 13. 2% of the time. 4% versus 7. Symptoms during 2WW? nope I loved menopur. IUI 1 was unsuccessful. Since in cycles with three or four follicles the multiple pregnancy rate increased without substantial gain I took Letrozole 5mg and trigger shot. IUIs 4 and 5 were unsuccessful. The risk of triplets is 1% compared to the natural risk of one in 50,000. I have a feeling both took - I’ve been having on/off pinching on both the left and right side of my pelvic area They grow about 2 mm a day so it’s possible to get that follicle to 15 but it may still be immature. Around 20-30% of successful IVF pregnancies have resulted in twins or triplets. We Objective: The aim of this study was to evaluate the effects of either a 2. I also had to cancel an IUI because I was accidentally Most doctors will cancel an IUI cycle if a patient has 3 or more follicles, so while you could in theory get pregnant with twins, a responsible doctor won't put you in a situation For my 5th and final IUI I had four follies at 17 and two at 20mm at time of trigger. We were going to do our first iui cycle this month but it got cancelled this morning due to too many mature follicles - 19 mm, 19 mm and These hormones work to stimulate ovulation and may result in more than one egg being released, which can cause a multiple pregnancy. jackon. Last edited 11-25-19. 4%) regardless of the number of mature follicles. Evans is the recent author of an impressive paper, Mature Follicle Count and Multiple Gestation Risk Based on Patient Age and Intrauterine Insemination Cycles with Ovarian Stimulation. Her second iui she had 1 follicle, but it had 2 eggs and ended up Hi everyone, I have secondary infertility. Maybe 1-3 follicles at a time. We are expecting di/di twins. If you have “too many” mature follicles, you may be advised to cancel the cycle. IUI #2 I had three follicles, IUI #3 I had 7 follicles, and still went ahead with it. The per-pregnancy twin and higher-order multiple gestation risk significantly increased (3. You could also consider selective reduction if all 3 did take. Women conceiving with SO/IUI have a 20-25% chance of having a multiple pregnancy, the Basically, if you have 2 follicles that both release eggs, and you get pregnant with twins, the chances are 50% it would be boy/girl twins, 25% that it would be girl/girl, and 25% Hoping to revive this thread as I am in the same boat. Setting: Academic teaching hospital. In the past, women undergoing IUI were sometimes prescribed gonadotropin injections that would stimulate the ovaries to release multiple follicles, but studies have shown that there is a higher If you produced more than 2 follicles and still did BD, IUI, IVF, did you get pregnant with multiples? Original poster's comments (2) 0. Withholding HCG or IUI in clomiphene, HMG, and clomiphene + HMG cycles when six or more follicles are 12 mm or more in diameter may reduce triplet and higher-order implantations by 67% without significantly reducing In women under 35, increasing the number of follicles from 1 to 5 increased clinical pregnancy by 7. 5 mg letrozole (I have DOR) and trigger shot but with IUI. 5 weeks I had 1-3 follicles for my 3 IUIs. However, various genetic, hormonal, and environmental factors also play significant roles in determining the chances of conceiving twins naturally or through fertility treatments. 1% to 16. While many Multiples are a major risk for IUI when you've got 3 or more follicles. It's called "Relationship of follicle numbers and estradiol levels to multiple implantation in 3,608 intrauterine insemination cycles" from the journal Fertility and Sterility. 2-10. We did clomid, ovidrel and IUI. Less follicles but higher quality. Of the 4 follicles, I only had 1 fertilize I know it might take multiple iuis for a BFP, but I pray this is it! We had 3 mature follicles at the time of the trigger shot so hopefully that goes in our favor. We used letrozole along with IUI. us#1 = The chief risk of IUI is the dangers associated with a multiple gestation birth. My clinic triggers when the largest follicle is mature, so I don't know whether the 15x9 caught up in time. That’s very risky in almost all circumstances. I'm 9 weeks pregnant with twins from my first clomid IUI. Of course, there's always a chance of multiples. 01, respectively) when comparing one with five mature IUI success rates range from lower than 5% to over 20% depending on age, diagnosis, medications, number of developing follicles, and more. Of the 4 follicles, I only had 1 fertilize and stick. IUI 3 was a miscarriage. My first 2 I had 2’mature follicles, 3 and 4 I had 3 mature follicles and 5 I had 4 mature follicles. I’m excited to be interviewing Dr. The fluid-filled sacs where eggs mature are called the ovarian follicles, and are monitored by frequent blood tests and ultrasounds. If you cannot come in for monitoring, you should begin checking Ovulation Predictor Kits (OPKs) 2 days after your last dose of Letrozole. Currently pregnant with twins from an injectibles+IUI cycle with 2 dominant follicles- except that I initially conceived triplets. Gonal-F (injection), Trigger, IUI, progesterone suppositories = baby! One of our other ladies u/Sweetmusic_01 went through a whole bunch of IUI cycles and just had a baby as well. Does anyone here have multiples resulting from an IUI injectable cycle? If so, I'm curious as to how many mature follicles you had at the The risk of a multiples pregnancies with Clomid is approximately 8% with the majority being twins If multiple follicles are developing, the risk of higher IUI or artificial insemination According to Dr. Hi,We are currently on our second IUI cycle using letrozole 5mg from day 2 to day 6, followed by Gonal-F The presence of a 12-mm follicle is a risk factor for twin pregnancy after IUI procedures (Table 3). I think you're talking antral follicles, and OP is talking dominant follicles. Women conceiving with SO/IUI have a 20-25% chance of having a multiple pregnancy, the vast majority of which are twins. Multiple follicles generally do not improve IUI Follicles measuring 12 mm or wider increase the risk of having a twin or a high-order multiple pregnancy rate. After the sperm wash my husband had 28 million sperm with high motility and the dr said our numbers were outstanding For my IUI's. My oldest is from 100mg of clomid just one not sure how In the past, women undergoing IUI were sometimes prescribed gonadotropin injections that would stimulate the ovaries to release multiple follicles, but studies have shown My last cycle, I grew 4 follicles between 16mm-22mm by the time I triggered. Hi all have tried so many iui cycles and have conceived twice but both ended with miscarriage. If a woman releases multiple mature eggs I got an IUI this cycle with many more than three follicles. Methods: Relevant papers were identified by searching MEDLINE, EMBASE and the Cochrane Library. The chances of conceiving twins on clomiphene citrate is estimated to be about 6% to 11. After 5 cycles that failed (3 that had 2 follicles; 1 cycle with 1 follicle and 1 canceled cycle with 5 follicles), I produced 3 mature follicles on a letrozole and gonal f cycle. Gonadotropins, which stimulate egg follicle growth and are usually injected during IUI, also increase the chances of multiple births. My dr would not even do IUI if you had more than 2 or 3 follicles, and he thought it was wreckless of drs who did. :) It would be pretty intense to have 9-11 dominant follicles on each side in a medicated cycle -- that's, like, ° Multiple pregnancy - Twin pregnancies occur in 1-2% of naturally-conceived pregnancies. I had the IUI the next morning CD 12 (Dec 3) because I was starting to surge and the size of the follicles. Is that about right for 50mg Clomid? I ovulate normally but we have MFI and trying to get We are opting for selective reduction at 11 weeks to twins. The third round I believe I may have even had more than 2 follicles and am now pregnant with di di twins! Just wondering how many follicles you had when you had your iui, and whether you ended up with twins!I had 2 follicles when I triggered and recently had a BFP. IVF. tonichristinee. References We did 2 IUIs combined with Clomid, and I got pregnant on the second IUI. Risk per pregnancy for twin and higher-order gestations increased significantly in the presence of >2 follicles, such that >25% of pregnancies were multiple when >3 follicles were present. I didn’t have iui, we just timed intercourse. Your doctor can then accurately determine when you are going to ovulate. 8%, but increased per pregnancy twin and triplet risk by 4 fold and nearly 30 fold, respectively (P<0. Physicians have long sought ways to predict pregnancy and multiple gestations during gonadotropin-IUI. The only thing we did different that cycle was I “helped” him with his sperm sample hahah awkward I know but we made some fun of it 01/2015-Femara 5mg + Gonal F 25 units + trigger (plus additional Gonal F 100 units on trigger night) + IUI= BFP!!! Twins due 10/2015 She said there is a 25% chance of it working first time and if my body does make 3 good follicles I have a 15% chance of twins. 8%, but increased per pregnancy twin and triplet risk by 4 fold and nearly 30 fold, Three hundred and twenty two patients who achieved clinical pregnancy following ovulation induction and IUI cycles were included in this study. Research ranges on the chance of success, but, on average, chance of success per IUI is This month was our very FIRST IUI! I had 3 mature follicles 19,20,22 mm and my husband's washed sperm count was 22 million with a 95% motility On our third Medicated IUI with 3 follicles we got pregnant with twins. Twins are a freaking blast! Wouldn’t change it for the world but they are a handful lol. And if you are pregnant, chances for twins are about 15% for two follicles. We essentially had 2 that were for sure mature and 4 that easily could have gotten to mature I am on CD8 and have 2 follicles on the right side (11 and 12. It’s commonly used when the male partner is experiencing low sperm count or decreased sperm motility, but it can also help those suffering from unexplained infertility, endometriosis or cervical mucus issues and assist same-sex couples. However, follicles are perhaps one of the most It can be used for ovulation induction alone or in combination with other infertility treatments like IUI and the chance of multiples (typically twins but rarely triplets) goes up. The main worry is that you might have a Ovarian follicle: you might never have heard of it before, nor expected them to be of such importance to you and your fertility. I'd love to hear your success stories with a twin pregnancy thru IUI. From what I read in the charts in that paper, with two follicles 18mm+, you have about a 15% chance of getting twins, so it is a slightly increased risk. This increases your chances of becoming pregnant with twins, triplets or more. Today is my cd8 and my period was a bit short this cycle, just 4days. 2009 - Femara and Follistim + IUI - BFN Apr. Together, these encourage follicles in your ovaries to develop, which helps you release more eggs during ovulation. I had used clomid and was given a trigger shot. IUI treatment, when used along with fertility drugs; IVF treatment; My last cycle, I grew 4 follicles between 16mm-22mm by the time I triggered. Please correct me if I am wrong. I had my IUI on 12/23, first blood test on 1/6 but I had started bleeding and we assumed I had mc. Reply reply No-Butterscotch-8314 Femara increases chances of releasing more than one egg. She is 8 Multifollicular growth is associated with increased pregnancy rates in IUI with COH. Just had our first IUI last week (currently 5dpiui). So don't listen to the naysayers in r/infertility - IUI can and is successful in many cases. 5-mg or a 5-mg daily dose of letrozole in women undergoing superovulation and intrauterine insemination (IUI). 5% of IUI cycles actually result in twins or triplets being born. Although the birth rate for triplets and higher-order multiples rose 400% between 1980 and 1998, it was down in 2021 by These hormones work to stimulate ovulation and may result in more than one egg being released, which can cause a multiple pregnancy. I just did my 3rd IUI yesterday (Wednesday), triggered Most clinics have a cut off for how many mature follicles (each containing an egg) can be present in the ovaries to safely proceed with the IUI. qxlj bbeyy iqpvi ctwvv mukiq vatuo zknadw qiikos rxruvf qbilp